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1

Human telomerase reverse transcriptase and glucose-regulated protein 78 increase the life span of articular chondrocytes and their repair potential

Masato Sato, Kazuo Shin-ya, Jeong Ik Lee, Miya Ishihara, Toshihiro Nagai, Nagatoshi Kaneshiro, Genya Mitani, Hidetoshi Tahara, Joji Mochida

Journal:

BMC Musculoskeletal Disorders

Year:

2012

Language:

english

File:

PDF, 405 KB

english, 2012

2

A new furaquinocin derivative, JBIR-136, from Streptomyces sp. 4963H2

Kawahara, Teppei, Nagai, Aya, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2012

Language:

english

File:

PDF, 403 KB

english, 2012

3

OTOF mutation analysis with massively parallel DNA sequencing in 2,265 Japanese sensorineural hearing loss patients

Iwasa, Yoh-ichiro, Nishio, Shin-ya, Sugaya, Akiko, Kataoka, Yuko, Kanda, Yukihiko, Taniguchi, Mirei, Nagai, Kyoko, Naito, Yasushi, Ikezono, Tetsuo, Horie, Rie, Sakurai, Yuika, Matsuoka, Rina, Takeda,

Journal:

Year:

2019

Language:

english

File:

PDF, 513 KB

english, 2019

4

ChemInform Abstract: Diheteropeptin, a New Substance with TGF-β-Like Activity, Produced by a Fungus, Diheterospora chlamydosporia. Part 1. Production, Isolation and Biological Activities.

Yuhta Masuoka, Kazuo Shin-ya, Yong-Bae Kim, Minoru Yoshida, Koji Nagai, Ken-Ichi Suzuki, Yoichi Hayakawa, Haruo Seto

Journal:

Year:

2001

File:

PDF, 30 KB

2001

5

ChemInform Abstract: Diheteropeptin, a Novel Substance with TGF-β-Like Activity, Produced by a Fungus, Diheterospora chlamydosporia. Part 2. Physicochemical Properties and Structure Elucidation.

Yuhta Masuoka, Kazuo Shin-ya, Kazuo Furihata, Hisao Matsumoto, Yukihiro Takebayashi, Koji Nagai, Ken-ichi Suzuki, Yoichi Hayakawa, Haruo Seto

Journal:

Year:

2001

File:

PDF, 28 KB

2001

6

ChemInform Abstract: Spiruchostatins A and B, Novel Gene Expression-Enhancing Substances Produced by Pseudomonas sp.

Yuhta Masuoka, Atsuko Nagai, Kazuo Shin-ya, Kazuo Furihata, Koji Nagai, Ken-ichi Suzuki, Yoichi Hayakawa, Haruo Seto

Journal:

Year:

2001

File:

PDF, 25 KB

2001

7

ChemInform Abstract: Phoenistatin, a New Gene Expression-Enhancing Substance Produced by Acremonium fusigerum.

Yuhta Masuoka, Kazuo Shin-Ya, Kazuo Furihata, Koji Nagai, Ken-ichi Suzuki, Yoichi Hayakawa, Haruo Seto

Journal:

Year:

2001

File:

PDF, 27 KB

2001

8

Oximidine III, a New Antitumor Antibiotic Against Transformed Cells from Pseudomonas sp. Part 2. Structure Elucidation.

Yoichi Hayakawa, Taijiro Tomikawa, Kazuo Shin-ya, Nakako Arao, Koji Nagai, Ken-ichi Suzuki, Kazuo Furihata

Journal:

Year:

2004

File:

PDF, 54 KB

2004

9

Oximidine III, a New Antitumor Antibiotic Against Transformed Cells from Pseudomonas sp. Part 1. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activity.

Yoichi Hayakawa, Taijiro Tomikawa, Kazuo Shin-Ya, Nakako Arao, Koji Nagai, Ken-ichi Suzuki

Journal:

Year:

2004

File:

PDF, 63 KB

2004

10

Structure of Tyroscherin, an Antitumor Antibiotic Against IGF-1-Dependent Cells from Pseudallescheria sp.

Yoichi Hayakawa, Tomoki Yamashita, Toshiya Mori, Koji Nagai, Kazuo Shin-ya, Hidenori Watanabe

Journal:

Year:

2005

File:

PDF, 16 KB

2005

11

ChemInform Abstract: Novel 24-Membered Macrolides, JBIR-19 (I) and -20 (II) Isolated from Metarhizium sp. fE61

Ikuko Kozone, Jun-ya Ueda, Machika Watanabe, Satoru Nogami, Aya Nagai, Shigeki Inaba, Yoshikazu Ohya, Motoki Takagi, Kazuo Shin-ya

Journal:

Year:

2009

File:

PDF, 16 KB

2009

12

ChemInform Abstract: JBIR-12 (I), a Novel Antioxidative Agent from Penicillium sp. NBRC 103941.

Miho Izumikawa, Aya Nagai, Takayuki Doi, Motoki Takagi, Kazuo Shin-ya

Journal:

Year:

2009

File:

PDF, 18 KB

2009

13

ChemInform Abstract: New Sesquiterpenes, JBIR-27 and -28, Isolated from a Tunicate-Derived Fungus, Penicillium sp. SS080624SCf1.

Keiichiro Motohashi, Junko Hashimoto, Shigeki Inaba, Shams Tabrez Khan, Hisayuki Komaki, Aya Nagai, Motoki Takagi, Kazuo Shin-ya

Journal:

Year:

2009

File:

PDF, 20 KB

2009

14

ChemInform Abstract: JBIR-44, a New Bromotyrosine Compound from a Marine Sponge Psammaplysilla purpurea

Takeshi Fujiwara, Ji-Hwan Hwang, Akihiko Kanamoto, Hiroshi Nagai, Motoki Takagi, Kazuo Shin-ya

Journal:

Year:

2010

File:

PDF, 13 KB

2010

15

ChemInform Abstract: JBIR-54, a New 4-Pyridinone Derivatives Isolated from Penicillium daleae Zaleski fE50.

Akira Mukai, Aya Nagai, Shigeki Inaba, Motoki Takagi, Kazuo Shin-ya

Journal:

Year:

2010

File:

PDF, 17 KB

2010

16

ChemInform Abstract: JBIR-69, a New Metabolite from Streptomyces sp. OG05.

Takeshi Fujiwara, Aya Nagai, Motoki Takagi, Kazuo Shin-ya

Journal:

Year:

2010

File:

PDF, 18 KB

2010

17

ChemInform Abstract: JBIR-83 and JBIR-84, New Promothiocin Derivatives, Isolated from Streptomyces sp. RI9.

Motoki Takagi, Keiichiro Motohashi, Aya Nagai, Junko Hashimoto, Kazuo Shin-ya

Journal:

Year:

2010

File:

PDF, 21 KB

2010

18

ChemInform Abstract: New Tensidols, JBIR-86 and JBIR-87, Isolated from Aspergillus sp. fJ80.

Motoki Takagi, Keiichiro Motohashi, Ji-Hwan Hwang, Aya Nagai, Kazuo Shin-ya

Journal:

Year:

2010

File:

PDF, 19 KB

2010

19

ChemInform Abstract: Isolation of 2 New Naphthablin Analogues, JBIR-79 (I) and JBIR-80 (II), from Streptomyces sp. RI24

Miho Izumikawa, Aya Nagai, Junko Hashimoto, Motoki Takagi, Kazuo Shin-ya

Journal:

Year:

2011

File:

PDF, 24 KB

2011

20

ChemInform Abstract: Two Novel Benzastatin Derivatives, JBIR-67 and JBIR-73, Isolated from Streptomyces sp. RI18.

Keiichiro Motohashi, Aya Nagai, Motoki Takagi, Kazuo Shin-ya

Journal:

Year:

2011

File:

PDF, 22 KB

2011

21

ChemInform Abstract: New Angucycline C-Glycosides from Streptomyces sp. RI33.

Jun-ya Ueda, Miho Izumikawa, Akira Mukai, Aya Nagai, Ji-Hwan Hwang, Motoki Takagi, Kazuo Shin-ya

Journal:

Year:

2011

File:

PDF, 26 KB

2011

22

Partitioning of chicken egg white proteins in polyelectrolyte/salt aqueous two-phase systems composed of polyethyleneoxide–maleic acid copolymer and potassium phosphate

Toshio Kajiuchi, Yoshitsune Shin-Ya, Hidetada Nagai, Koichi Fujiwara

Journal:

Journal of Chemical Technology & Biotechnology

Year:

2002

Language:

english

File:

PDF, 106 KB

english, 2002

23

Spiruchostatins A and B, novel gene expression-enhancing substances produced by Pseudomonas sp.

Yuhta Masuoka, Atsuko Nagai, Kazuo Shin-ya, Kazuo Furihata, Koji Nagai, Ken-ichi Suzuki, Yoichi Hayakawa, Haruo Seto

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 81 KB

english, 2001

24

Thioviridamide, a Novel Apoptosis Inducer in Transformed Cells from Streptomyces olivoviridis

Hayakawa, Yoichi, Sasaki, Kahori, Adachi, Hisashi, Furihata, Keiko, Nagai, Koji, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2006

Language:

english

File:

PDF, 149 KB

english, 2006

25

Structure of Thioviridamide, a Novel Apoptosis Inducer from Streptomyces olivoviridis

Hayakawa, Yoichi, Sasaki, Kahori, Nagai, Koji, Shin-ya, Kazuo, Furihata, Kazuo

Journal:

The Journal of Antibiotics

Year:

2006

Language:

english

File:

PDF, 164 KB

english, 2006

26

Burkholone, A New Cytotoxic Antibiotic against IGF-I Dependent Cells from Burkholderia sp.

Mori, Toshiya, Yamashita, Tomoki, Furihata, Kazuo, Nagai, Koji, Suzuki, Ken-ichi, Hayakawa, Yoichi, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2007

Language:

english

File:

PDF, 92 KB

english, 2007

27

A Novel Antimycin-like Compound, JBIR-06, from Streptomyces sp. ML55

Ueda, Jun-ya, Nagai, Aya, Izumikawa, Miho, Chijiwa, Shuhei, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2008

Language:

english

File:

PDF, 96 KB

english, 2008

28

JBIR-54, a new 4-pyridinone derivative isolated from Penicillium daleae Zaleski fE50

Mukai, Akira, Nagai, Aya, Inaba, Shigeki, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 143 KB

english, 2009

29

JBIR-69, a new metabolite from Streptomyces sp. OG05

Fujiwara, Takeshi, Nagai, Aya, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 176 KB

english, 2010

30

JBIR-12, a novel antioxidative agent from Penicillium sp. NBRC 103941

Izumikawa, Miho, Nagai, Aya, Doi, Takayuki, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 125 KB

english, 2009

31

Novel 24-membered macrolides, JBIR-19 and -20 isolated from Metarhizium sp. fE61

Kozone, Ikuko, Ueda, Jun-ya, Watanabe, Machika, Nogami, Satoru, Nagai, Aya, Inaba, Shigeki, Ohya, Yoshikazu, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 139 KB

english, 2009

32

New sesquiterpenes, JBIR-27 and -28, isolated from a tunicate-derived fungus, Penicillium sp. SS080624SCf1

Motohashi, Keiichiro, Hashimoto, Junko, Inaba, Shigeki, Khan, Shams Tabrez, Komaki, Hisayuki, Nagai, Aya, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 120 KB

english, 2009

33

JBIR-44, a new bromotyrosine compound from a marine sponge Psammaplysilla purpurea

Fujiwara, Takeshi, Hwang, Ji-Hwan, Kanamoto, Akihiko, Nagai, Hiroshi, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 125 KB

english, 2009

34

Two novel benzastatin derivatives, JBIR-67 and JBIR-73, isolated from Streptomyces sp. RI18

Motohashi, Keiichiro, Nagai, Aya, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2011

Language:

english

File:

PDF, 244 KB

english, 2011

35

New tensidols, JBIR-86 and JBIR-87, isolated from Aspergillus sp. fJ80

Takagi, Motoki, Motohashi, Keiichiro, Hwang, Ji-Hwan, Nagai, Aya, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 202 KB

english, 2010

36

JBIR-83 and JBIR-84, new promothiocin derivatives, isolated from Streptomyces sp. RI19

Takagi, Motoki, Motohashi, Keiichiro, Nagai, Aya, Hashimoto, Junko, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 280 KB

english, 2010

37

New angucycline C-glycosides from Streptomyces sp. RI33

Ueda, Jun-ya, Izumikawa, Miho, Mukai, Akira, Nagai, Aya, Hwang, Ji-Hwan, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2011

Language:

english

File:

PDF, 414 KB

english, 2011

38

Effects of 2-alkynyladenosine derivatives on intraocular pressure in rabbits

Takashi Konno, Shin-ya Ohnuma, Kazuhiro Uemoto, Takehiro Uchibori, Akihiko Nagai, Kentaro Kogi, Kazuki Endo, Tomokazu Hosokawa, Norimichi Nakahata

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 861 KB

english, 2004

39

Naphthoquinone-like Polyketide Isolated from Streptomyces sp. RI-77 and Its Predicted Biosynthetic Pathway

Izumikawa, Miho, Satou, Ryutaro, Motohashi, Keiichiro, Nagai, Aya, Ohnishi, Yasuo, Takagi, Motoki, Shin-ya, Kazuo

Journal:

Journal of Natural Products

Year:

2011

Language:

english

File:

PDF, 323 KB

english, 2011

40

Nerve growth factor attenuates 2-deoxy-d-glucose-triggered endoplasmic reticulum stress-mediated apoptosis via enhanced expression of GRP78

Soichiro Kishi, Koji Shimoke, Yosuke Nakatani, Takafumi Shimada, Nobuaki Okumura, Katsuya Nagai, Kazuo Shin-ya, Toshihiko Ikeuchi

Journal:

Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 557 KB

english, 2010

41

Direct visualization of affected collagen molecules synthesized by cultured fibroblasts from an osteogenesis imperfecta patient

Kunihiko Kobayashi, Ryu-ichiro Hata, Shin-ya Nagai, Jun-ichi Niwa, Takeshi Hoshino

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 3.66 MB

english, 1990

42

Anti-Influenza Virus Compound from Streptomyces sp. RI18

Takagi, Motoki, Motohashi, Keiichiro, Nagai, Aya, Izumikawa, Miho, Tanaka, Masahiro, Fuse, Shinichiro, Doi, Takayuki, Iwase, Keiichiro, Kawaguchi, Atsushi, Nagata, Kyosuke, Takahashi, Takashi, Shin-ya

Journal:

Organic Letters

Year:

2010

Language:

english

File:

PDF, 197 KB

english, 2010

43

JBIR-137 and JBIR-138, new secondary metabolites from Aspergillus sp. fA75

Kawahara, Teppei, Nagai, Aya, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2012

Language:

english

File:

PDF, 842 KB

english, 2012

44

Isolation of 2 new naphthablin analogs, JBIR-79 and JBIR-80, from Streptomyces sp. RI24

Izumikawa, Miho, Nagai, Aya, Hashimoto, Junko, Takagi, Motoki, Shin-ya, Kazuo

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 204 KB

english, 2010

45

OTOFmutation screening in Japanese severe to profound recessive hearing loss patients

Iwasa, Yoh-ichiro, Nishio, Shin-ya, Yoshimura, Hidekane, Kanda, Yukihiko, Kumakawa, Kozo, Abe, Satoko, Naito, Yasushi, Nagai, Kyoko, Usami, Shin-ichi

Journal:

BMC Medical Genetics

Year:

2013

Language:

english

File:

PDF, 281 KB

english, 2013

46

JBIR-37 and -38, Novel Glycosyl Benzenediols, Isolated from the Sponge-Derived Fungus, Acremonium sp. SpF080624G1f01

IZUMIKAWA, Miho, KHAN, Shams Tabrez, KOMAKI, Hisayuki, NAGAI, Aya, INABA, Shigeki, TAKAGI, Motoki, SHIN-YA, Kazuo

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2009

Language:

english

File:

PDF, 71 KB

english, 2009

47

Streptomyces aomiensis sp. nov., isolated from a soil sample using the membrane-filter method

Nagai, A., Khan, S. T., Tamura, T., Takagi, M., Shin-ya, K.

Journal:

INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Year:

2011

Language:

english

File:

PDF, 109 KB

english, 2011

48

Acid Catalyzed Hydrolysis of Ciclic Benzophenone Acetals. Effects of Ring Size and Ring Substituent

Oshima, Takumi, Ueno, Shin-ya, Nagai, Toshikazu

Journal:

Year:

1995

Language:

english

File:

PDF, 250 KB

english, 1995

49

Isolation and structural elucidation of pyridoxatin, a free radical scavenger of microbial origin.

TESHIMA, YOSHIHIRO, SHIN-YA, KAZUO, SHIMAZU, AKIRA, FURIHATA, KEIKO, CHUL, HA SANG, FURIHATA, KAZUO, HAYAKAWA, YOICHI, NAGAI, KAZUO, SETO, HARUO

Journal:

The Journal of Antibiotics

Year:

1991

Language:

english

File:

PDF, 194 KB

english, 1991

50

Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neurons from Excitotoxicity. II. Structure Determination.

KOBAYASHI, HIROYUKI, SHIN-YA, KAZUO, FURIHATA, KAZUO, NAGAI, KOJI, SUZUKI, KEN-ICHI, HAYAKAWA, YOICHI, SETO, HARUO, YUN, BONG-SIK, RYOO, IN-JA, KIM, JUNG-SIK, KIM, CHANG-JIN, YOO, ICK-DONG

Journal:

The Journal of Antibiotics

Year:

2001

Language:

english

File:

PDF, 311 KB

english, 2001

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